Three Game-Changing ‘General Hospital’ Moments the Week of Sept 29

General Hospital spoilers reveal there are three must-see moments for the week of September 29, 2025. Fans can expect dramatic consequences during Monica Quartermaine’s (Lesley Charleson) will reading.
Portia Robinson (Brook Kerr) gets life-changing news. Plus, Nina Reeves (Cynthia Watros) continues trying to play peacemaker with Britt Westbourne (Kelly Thiebaud) and Liesl Obrecht (Kathleen Gati). Keep reading and let’s talk about what is coming up in the ABC soap opera.
Monica Quartermaine’s Will Reading
Let’s start off with Monica’s will. Drew Cain (Cameron Mathison) was pretty insistent on attending Monica’s funeral, but was booted out by Tracy Quartermaine (Jane Elliott). Then, Drew made a vow to Martin Grey (Michael E. Knight).
Meanwhile, we have Veronica “Ronnie” Bard (Erika Slezak), who has turned up in Port Charles. Tracy wasn’t pleased to see her. That will continue as Tracy deals with her new houseguest. However, I am also wondering why Ronnie has turned up right before the will reading. I actually don’t think that’s a coincidence.
Nina Reeves’ Peacekeeping
Next up, we have Nina, who will continue trying to keep the peace between Britt and Liesl. The two are not getting along and things have just gotten worse. In the upcoming week, one must-see moment includes Nina mediating. Nina reminds the mother and daughter that they will need each other during this Nathan West (Ryan Paevey) situation.
Portia Robinson’s Life-Changing News
General Hospital spoilers for the week of September 29 reveal that another must-see moment has to do with Portia. It is stated that at the end of the week, she gets life-changing news. I don’t think she’s pregnant, so could this be about Drew’s shooting or even about Heather Webber (Alley Mills)?
At one point next week, Curtis Ashford (Donnell Turner) shares his theory with Portia. So, I wonder if Portia will get blamed for the shooting, and maybe it’s up to Curtis to clear her name? They might be over, but Curtis still cares about her as a person. Curtis also won’t want to let down Trina Robinson (Tabyana Ali).

Speaking of, Trina and Kai Taylor (Jens Austin Astrup) could continue to worry about the prints on the bat.
Gio Palmieri’s Big Decision
There is also Gio Palmieri (Giovanni Mazza). Next week, the young man makes a big decision. Could he finally decide to forgive his family? Is he finally ready to get to know Dante Falconeri (Dominic Zamprogna) and Brook Lynn Quartermaine (Amanda Setton) as his bio parents? While the young man was furious for months, he does seem to have thawed, so stay tuned!
Which storyline are you looking forward to seeing the most during the week of September 29, 2025? Share your thoughts in the comment section below. Remember to keep watching the soap on ABC to find out what happens next.

[…] Maxie and Spinelli were good until she got pregnant and didn’t tell him after she lost Lulu Spencer (Alexa Havins) and Dante Falconeri (Dominic Zamprogna) baby. […]