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3 Must-See ‘General Hospital’ Moments – Week of April 21

General Hospital spoilers reveal there are three must-see moments for the week of April 21, 2025. Fans can expect Jenz Sidwell (Carlo Rota) to advise Alexis Davis (Nancy Lee Grahn). Sonny Corinthos (Maurice Benard) has his heart surgery.

Plus, Drew Cain’s (Cameron Mathison) reaction surprises Willow Tait-Corinthos (Katelyn MacMullen). This could be connected to Nina Reeves (Cynthia Watros) playing dirty later in the week, so let’s get started.

Jenz Sidwell’s Surprise

At the law office, Alexis will get a surprise when Sidwell comes to see her. The decision about Marco Rios’ (Adrian Anchondo) fate at the law office isn’t clear yet. It certainly doesn’t look good that Sidwell is Marco’s father.

Now, right after that, Sidwell shows up and tells her that the law firm would be foolish not to hire his son. It doesn’t look good for Marco, that’s for sure. Maybe that’s exactly what Sidwell wants Alexis and Diane Miller (Carolyn Hennesy) to think.

Sonny Corinthos’ Heart Surgery

Another must-see moment next week centers on Sonny’s heart surgery. Sonny has been trying to keep his condition a secret from most people. Now that the surgery is coming up, he’s finally informing Carly Spencer (Laura Wright). Carly is insisting on accompanying Sonny to the surgery, which is probably a good thing. 

However, the problem is that Natalia Ramirez (Eva LaRue) insisted to Sonny that she didn’t even speak to her ex-husband.

However, right after that, Natalia blurted out that Sonny has surgery coming up. Natalia might have said it out of fear or anxiety, but now Sidwell can strike the mob boss when he is at his weakest.

Drew Cain’s Reaction

General Hospital spoilers reveal that Drew will have a certain reaction to something. It causes Willow to immediately take notice. It sounds like Drew’s mask might be starting to fall off.

It’s about time that Willow sees his true colors. However, she had already signed those papers giving him her kids just in case. 

This keeps coming back in my mind. I don’t think Willow is going to get killed off right now, but perhaps Drew uses those legal papers in a troubling way. The documents might not just cover death, but mental illness as well. Drew seems like the type of man that would totally gaslight a lover to keep her from exposing his secrets. 

Nina Reeves’ Plays Dirty

At the end of the week, Nina plays dirty. Fans know she is desperate to protect her daughter and grandchildren from Drew. What will Nina do and will it save Willow, or just make things worse?

Which storyline are you looking forward to seeing the most? Share your thoughts in the comment section below. Remember to keep watching the soap on ABC to find out what is coming up next.

Amandah Hancen: Taylor has watched Days of Our Lives for 25 years and loves to read, write and breath the soap. When not watching Salemite shenanigans, she enjoys reading mystery novels, listening to music, laughing at her own jokes and exploring the great outdoors. She also spends plenty of quality time with her kids and Pitbull Doxie, Pongolicous Pongo Puff.

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